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What Causes Bile Duct 슬롯 사이트?

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We don¡¯t know the exact cause of most bile duct cancers, but we do know some of the risk factors that make a person more likely to develop these cancers.

There seems to be a link between bile duct cancer and things that irritate and inflame the bile ducts, whether it¡¯s bile duct stones, infection with a parasite, or something else.

Scientists are starting to understand how inflammation might lead to certain changes in the DNA of cells, making them grow out of control and form cancers. DNA is the chemical in each of our cells that makes up our genes (the instructions for how our cells function).

  • Genes that control when cells grow, divide into new cells, and die are called oncogenes.
  • Genes that slow down cell division or cause cells to die at the right time are called tumor suppressor genes.

슬롯 사이트s can be caused by DNA changes (mutations) that turn on oncogenes or turn off tumor suppressor genes. Changes in many different genes are usually needed for a cell to become cancer.

We usually look like our parents because they are the source of our DNA. But DNA affects more than how we look. Some people inherit DNA mutations from their parents that greatly increase their risk for certain cancers.

There are few known genetically inherited disorders that are associated with higher risk for bile duct cancer. Gene mutations related to bile duct cancers are usually acquired during life rather than inherited. For example, acquired changes in the TP53 tumor suppressor gene are found in most bile duct cancers. Other genes that may play a role in bile duct cancers include KRAS, HER2, and ALK.

Some of the gene changes that lead to bile duct cancer might be caused by inflammation. But sometimes the cause of these changes is not known. Many gene changes might just be random events that sometimes happen inside a cell, without having an outside cause.

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Developed by the 슬롯사이트 - 프라그마틱 무료 슬롯 게임 사이트 medical and editorial content team with medical review and contribution by the 무료슬롯 슬롯 게임 of Clinical Oncology (ASCO).

Abou-Alfa GK, Jarnagin W, Lowery M, D¡¯Angelica M, Brown K, Ludwig E, Covey A, Kemeny N, Goodman KA, Shia J, O¡¯Reilly EM. Liver and bile duct cancer. In: Neiderhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff¡¯s Clinical Oncology. 5th ed. Philadelphia, PA. Elsevier; 2014:1373-1395.

National 슬롯 사이트 Institute. Bile Duct 슬롯 사이트 (Cholangiocarcinoma) Symptoms, Tests, Prognosis, and Stages (PDQ?)¨CPatient Version. May 24, 2024. Accessed at www.cancer.gov/types/liver/patient/about-bile-duct-cancer-pdq on August 19, 2024.Patel T, Borad MJ. Carcinoma of the biliary tree. In: DeVita VT, Lawrence TS, Rosenberg SA, eds. DeVita, Hellman, and Rosenberg¡¯s 슬롯 사이트: Principles and Practice of Oncology. 10th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2015:715-735.

Last Revised: October 11, 2024

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