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Chemotherapy (chemo) uses anti-cancer drugs that are usually given intravenously (IV or into a vein), by mouth, or applied to the skin in other ways, such as in an ointment. Drugs taken by mouth or injected into a vein, called systemic chemo, enter the bloodstream and go throughout the body, making this treatment potentially useful for cancer that has spread beyond the vulva.
In more advanced disease, chemo might be given with radiation therapy before surgery. Chemotherapy helps radiation work better, and this may shrink the tumor so it's easier to remove. At this time, chemo is most often used for vulvar cancers that have spread or have come back after surgery.
The role of chemo in treating vulvar cancer is not clear. There are no standard chemo treatment plans.
For earlier-stage vulvar cancer, chemo may be given with radiation (chemoradiation). This chemo is usually cisplatin or carboplatin. More advanced vulvar cancers may be treated with a combination of the following chemo drugs:
Different drugs are used to treat vulvar melanoma. Melanoma Skin 슬롯 사이트 has more information on drug treatment for advanced melanomas.
Many chemo drugs work by attacking cells that are rapidly dividing. This is helpful in killing cancer cells, but these drugs can also affect normal cells, leading to side effects. Side effects of chemo depend on the type of drugs, the amount taken, and the length of time you are treated. Common side effects of some of the drugs used to treat vulvar cancer include:
Chemo often affects the blood-forming cells of the bone marrow, leading to low blood counts. This can cause:
Other side effects depend on what drug is used. Most side effects stop when the treatment is over, but some chemo drugs can have long-lasting or even permanent effects. For instance, cisplatin can cause nerve damage (called neuropathy). This can lead to numbness, tingling, or even pain in the hands and feet. Cisplatin can also damage the kidneys. To lower the risk of kidney damage, plenty of fluids are given intravenously (IV) before and after each dose.
Ask your cancer care team about the chemo drugs you'll get and what side effects you can expect. Also, be sure to tell them about any side effects you do have so they can be treated. For example, you can be given medicine to reduce or prevent nausea and vomiting.
For more general information about how chemotherapy is used to treat cancer, see Chemotherapy.
To learn about some of the side effects listed here and how to manage them, see Managing 슬롯 사이트-related Side Effects.
Developed by the 슬롯사이트 - 프라그마틱 무료 슬롯 게임 사이트 medical and editorial content team with medical review and contribution by the 무료슬롯 슬롯 게임 of Clinical Oncology (ASCO).
Chargari C, Wasserman J, Gabro A, Canlobre G, Spano JP, Uzan C, Maingon P. Vulvar Carcinoma: Standard of Care and Perspectives. J Clin Oncol. 2024 Mar 10;42(8):961-972.
National 슬롯 사이트 Institute. Vulvar 슬롯 사이트 Treatment (PDQ?)¨CPatient Version. September 18, 2024. Accessed at www.cancer.gov/types/vulvar/patient/vulvar-treatment-pdq#section/_90 on February 17, 2025.
National Comprehensive 슬롯 사이트 Network. NCCN Clinical Guidelines in Oncology (NCCN Guidelines). Vulvar 슬롯 사이트 (Squamous Cell Carcinoma) Version 1.2025 ¨C Feb 10, 2025.
Olawaiye AB, Cuello MA, Rogers LJ. 슬롯 사이트 of the vulva: 2021 update. Int J Gynaecol Obstet. 2021 Oct;155 Suppl 1(Suppl 1):7-18.
Last Revised: May 2, 2025
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